This is a problem that's happening intermittently which makes it difficult to pinpoint. I will give you an example though. I pull up photo 5847 in the develope module. I go over to my presets and select Portra 400 Canon Standard. The preset is highlighted however no adjustments are made to image 5847. I then click to another preset, the image then adjusts to those settings for the new preset I've clicked, but it never will adjust on the first click of that original desired preset. I'm wondering if it has something to do with the preview loading - however I build 1:1 previews before working on any of the files.
It would be impossible for me to screen shot the changes that are happening when clicking between images - it happens completely at random - often when I'm not even touching the computer. I've used Lightroom very comfortably for years so these sudden changes to files without me actually doing anything on the keyboard or mouse are baffling as one might imagine.